Cell Lines and Cell Cultures
iXCells Biotechnologies Rat Pulmonary Microvascular En
Rat Pulmonary Microvascular Endothelial Cells (RPMEC)
Cell Biologics C57 CARDIAC ENDOTHELIAL CELLS
C57BL/6 MOUSE PRIMARY CARDIAC MICROVASCULAR ENDOTHELIAL CELLS - Frozen Vial
iXCells Biotechnologies Human Neural Stem Cells iPSCde
Human Neural Stem Cells (iPSC-derived, Amyotrophic Lateral Sclerosis Patient, Sporadic)
iXCells Biotechnologies Human Peripheral Blood CD8 Cyt
Human Peripheral Blood CD8+ Cytotoxic T Cells
iXCells Biotechnologies Human Peripheral Blood Pan Mon
Human Peripheral Blood Pan Monocytes - Untouched
Genscript Corporation CHO-K1/cyno TIGIT Stable Cell
TIGIT (T cell immunoreceptor with Ig and ITIM domains) was recently characterized as an inhibitory receptor which is expressed mainly on NK Treg CD8 T and CD4 T cells TIGIT harbors an immunoglobulin tail tyrosine (ITT)-like phosphorylation motif and an ITIM (immunoreceptor tyrosine-based inhibition motif) in its cytoplasmic tail The poliovirus receptor (PVR or CD155) was identified as the physical ligand of TIGIT with high affinity and PVRL2 (Nectin2 or CD112) also binds to TIGIT with a weaker binding capacity TIGIT/PVR engagement suppresses T cell activation through IL-10 secretion mediated by dendritic cells Furthermore TIGIT also exerts an intrinsic inhibitory function to T cell activation
